Scar Prevention in Asians

A randomised, placebo-controlled, double-blind prospective clinical trial evaluated the efficacy of Dermatix^® in the prevention of hypertrophic scar development in median sternotomy wounds in 50 patients.
Each patient's wound was divided into half control and half intervention wound. Upper and lower halves were randomised by an independent pharmacist. Silicone gel was applied twice daily from the second week to the third post-operative month in the intervention group.

"This well-conducted, rigorous study provides convincing evidence for the efficacy of an applied silicone gel in preventing median sternotomy hypertrophic scars in an Asian population." ^[2]

Significant differences were observed between the Dermatix^® group and the control group in all parameters: ^[1]

1. Chan KY et al. Plast Reconstr Surg. 2005; 116: 1013-20
2. Mustoe TA. Plastic Reconstr Surg 2005; 116: 1013-20